Rentschler KM, Milosavljevic S, Baratta AM, Wright CJ, Piroli MV, Tentor Z, Valafar H, O’Reilly C, Pocivavsek A. Reducing brain kynurenic acid precludes kynurenine-induced sleep disturbances. Journal of Sleep Research. 2024 May;33(3):e14038. doi: 10.1111/jsr.14038.
2023
Wright CJ, Milosavljevic S, Pocivavsek A. The stress of losing sleep: Sex-specific neurobiological outcomes. Neurobiol Stress. 2023. Doi: 10.1016/j.ynstr.2023.100543.
Milosavljevic S, Smith AK, Wright CJ, Valafar H, Pocivavsek A. Kynurenine aminotransferase II inhibition promotes sleep and rescues impairments induced by neurodevelopmental insult. Translational Psychiatry. 2023. 13:106; https://doi.org/10.1038/s41398-023-02399-1
2021
Smith A, Anand H, Milosavljevic S, Rentschler KM, Pocivavsek A, Valafar H. Application of Machine Learning to Sleep Stage Classification. 2021 International Conference on Computational Science and Computational Intelligence (Csci 2021).349-354.
Wright CJ, Rentschler KM, Wagner NTJ, Lewis AM, Beggiato S, Pocivavsek A. Time of day-dependent alterations in hippocampal kynurenic acid, glutamate, and GABA in adult rats exposed to elevated kynurenic acid during neurodevelopment. Front Psychiatry. 2021 Sep 17;12:734984. doi:10.3389/fpsyt.2021.734984. eCollection 2021.
Rentschler KM, Baratta AM, Ditty AL, Wagner NTJ, Wright CJ, Milosavljevic S, Mong JA, Pocivavsek A. Prenatal kynurenine elevation elicits sex-dependent changes in sleep and arousal during adulthood: Implications for psychotic disorders. Schizophr Bull. 2021 Aug 21;47(5):1320-1330. Doi: 10.1093/schbul/sbab029.
2020
Buck SA, Baratta AM, Pocivavsek A. Exposure to elevated embryonic kynurenine in rats: Sex-dependent learning and memory impairments in adult offspring. Neurobiol Learn Mem. 2020 Jul 30;174:107282. Doi: 10.1016/j.nlm.2020.107282.
Baratta AM, Kanyuch NR, Cole CA, Valafar H, Deslauriers J, Pocivavsek A. Acute sleep deprivation during pregnancy in rats: Rapid elevation of placental and fetal inflammation and kynurenic acid. Neurobiol Stress. 2019 Dec 14;12:100204. Doi: 10.1016/j.ynstr.2019.100204. eCollection 2020 May.
2019
Pocivavsek A, Elmer GI, Schwarcz R. (2019) Inhibition of kynurenine aminotransferase II attenuates hippocampus-dependent memory deficit in adult rats treated prenatally with kynurenine. Hippocampus. 29(2):73-77.
2018
Baratta A.M., Viechweg S.S., Mong J.A., Pocivavsek A. (2018) A High-performance Liquid Chromatography Measurement of Kynurenine and Kynurenic Acid: Relating Biochemistry to Cognition and Sleep in Rats. J Vis Exp. 19;(138).
Notarangelo F.M., Pocivavsek A., Schwarcz R. (2018) Exercise Your Kynurenines to Fight Depression. Trends Neurosci. 41(8):491-493.
Chiappelli J., Rowland L.M., Notarangelo F.M., Wijtenburg S.A., Thomas M.A.R., Pocivavsek A., Jones A., Wisner K., Kochunov P., Schwarcz R., Hong L.E. (2018) Salivary kynurenic acid response to psychological stress: inverse relationship to cortical glutamate in schizophrenia. Neuropsychopharmacology. 43(8):1706-1711.
Baratta, A.M., Buck, S.A., Buchla, A.D., Fabian, C.B., Chen, S., Mong, J.A., & Pocivavsek, A. (2018) Sex Differences in Hippocampal Memory and Kynurenic Acid Formation Following Acute Sleep Deprivation in Rats. Scientific Reports, 8(1):6963.
2017
Pocivavsek, A., & Rowland, L. M. (2017). Basic Neuroscience Illuminates Causal Relationship between Sleep and Memory: Translating to Schizophrenia. Schizophrenia Bulletin, 44(1), 7-14
Pocivavsek, A., Baratta, A. M., Mong, J. A., & Viechweg, S. S. (2017). Acute Kynurenine Challenge Disrupts Sleep–Wake Architecture and Impairs Contextual Memory in Adult Rats. Sleep, 40(11), zsx141.
Hahn, B., Reneski, C. H., Pocivavsek, A., & Schwarcz, R. (2017). Prenatal kynurenine treatment in rats causes schizophrenia-like broad monitoring deficits in adulthood. Psychopharmacology, 1-11.
Erhardt, S., Pocivavsek, A., Repici, M., Liu, X. C., Imbeault, S., Maddison, D. C., ... & Giorgini, F. (2017). Adaptive and behavioral changes in kynurenine 3-monooxygenase knockout mice: relevance to psychotic disorders. Biological Psychiatry, 82(10), 756-765.
Notarangelo, F. M., & Pocivavsek, A. (2017). Elevated kynurenine pathway metabolism during neurodevelopment: implications for brain and behavior. Neuropharmacology, 112, 275-285.
2016
Clark, S. M., Pocivavsek, A., Nicholson, J. D., Notarangelo, F. M., Langenberg, P., McMahon, R. P., ... & Schwarcz, R. (2016). Reduced kynurenine pathway metabolism and cytokine expression in the prefrontal cortex of depressed individuals. Journal of Psychiatry & Neuroscience: JPN, 41(6), 386.
Pershing, M. L., Phenis, D., Valentini, V., Pocivavsek, A., Lindquist, D. H., Schwarcz, R., & Bruno, J. P. (2016). Prenatal kynurenine exposure in rats: age-dependent changes in NMDA receptor expression and conditioned fear responding. Psychopharmacology, 233(21-22), 3725-3735.
2015
Pershing, M. L., Bortz, D. M., Pocivavsek, A., Fredericks, P. J., Jørgensen, C. V., Vunck, S. A., ... & Bruno, J. P. (2015). Elevated levels of kynurenic acid during gestation produce neurochemical, morphological, and cognitive deficits in adulthood: implications for schizophrenia. Neuropharmacology, 90, 33-41.
2014
Pocivavsek, A., Thomas, M. A., Elmer, G. I., Bruno, J. P., & Schwarcz, R. (2014). Continuous kynurenine administration during the prenatal period, but not during adolescence, causes learning and memory deficits in adult rats. Psychopharmacology, 231(14), 2799-2809.
Chiappelli, J., Pocivavsek, A., Nugent, K. L., Notarangelo, F. M., Kochunov, P., Rowland, L. M., ... & Hong, L. E. (2014). Stress-induced increase in kynurenic acid as a potential biomarker for patients with schizophrenia and distress intolerance. JAMA Psychiatry, 71(7), 761-768.
Wu, H. Q., Okuyama, M., Kajii, Y., Pocivavsek, A., Bruno, J. P., & Schwarcz, R. (2014). Targeting kynurenine aminotransferase II in psychiatric diseases: promising effects of an orally active enzyme inhibitor. Schizophrenia Bulletin, 40(Suppl_2), S152-S158.
2013
Alexander, K. S., Pocivavsek, A., Wu, H. Q., Pershing, M. L., Schwarcz, R., & Bruno, J. P. (2013). Early developmental elevations of brain kynurenic acid impair cognitive flexibility in adults: reversal with galantamine. Neuroscience, 238, 19-28.
2012
Pocivavsek, A., Wu, H. Q., Elmer, G. I., Bruno, J. P., & Schwarcz, R. (2012). Pre‐and postnatal exposure to kynurenine causes cognitive deficits in adulthood. European Journal of Neuroscience, 35(10), 1605-1612.
2011
Pocivavsek, A., Wu, H. Q., Potter, M. C., Elmer, G. I., Pellicciari, R., & Schwarcz, R. (2011). Fluctuations in endogenous kynurenic acid control hippocampal glutamate and memory. Neuropsychopharmacology, 36(11), 2357.
Full list of publications: http://www.ncbi.nlm.nih.gov/sites/http://www.ncbi.nlm.nih.gov/sites/myncbi/ana.pocivavsek.1/bibliography/50004215/public/?sort=date&direction=ascending/ana.pocivavsek.1/bibliography/50004215/public/?sort=date&direction=ascending
